Abstract In 2008 the Food and Drug Specialty Products Administration introduced a guidance for industry that requires the investigation of cardiovascular outcomes of glucose-lowering medications.Since then, an increasing number of cardiovascular outcome trials have been completed in diabetes patients with high cardiovascular risk for members of the
Deficiency in human mitochondrial Complex-1 has been linked to a wide variety of neurological disorders.Homozygous deletion of the Complex-1 associated protein, Ndufaf2, leads to a severe juvenile onset encephalopathy involving degeneration of the substantia nigra and other sub-cortical regions resulting in adolescent lethality.To understand the pr
During the summer a thermal low-pressure system is locked over the Iberian Peninsula.We Carb Cap present a first analysis of such a system using the potential vorticity approach.Our results show that its main characteristic is the existence of a negative potential vorticity (PV) dome and a funnel-like structure for potential temperature, both locat
To overcome the common shortcomings shared by the existing methods: weak suppression noise interference and feeble performance of time-frequency concentration,a novel time-frequency analysis method based on sparse repre-sentation was developed,which could get clear and concentrate time-frequency representation.Firstly,the Full Panel Bed unconstrain
ABSTRACT Coronavirus disease 2019 (COVID-19) has wreaked havoc across the globe; although the number of cases in Africa remains lower than in other regions, it is on a gradual upward trajectory.To date, COVID-19 cases have been reported in 54 out of 55 African Default countries.However, due to limited severe acute respiratory syndrome coronavirus 2